CD24 Mouse Monoclonal Antibody [Clone ID: SN3]

CAT#: AM03032RP-N

CD24 mouse monoclonal antibody, clone SN3, PE

Conjugation: Unconjugated APC FITC PE



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CNY 4,340.00


货期*
5周

规格
    • 100 Tests

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Specifications

Product Data
Clone Name SN3
Applications FC
Recommend Dilution Flow Cytometry analysis of Human blood cells using 20 ?l reagent / 100 ?l of whole blood or 106 cells in a suspension. 
The content of a vial (2 ml) is sufficient for 100 tests.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Glycoproteins purified from Human NALM-1 cell line
Specificity The antibody SN3 reacts with CD24, a 35-45 kDa heavily glycosylated cell surface antigen. CD24 is expressed by granulocytes, B lymphocytes and by some activated T cells and T cell malignancies. It is not expressed on Human thymocytes.
Formulation PBS
Label: PE
State: Liquid purified Ig fraction
Preservative: 15 mM Sodium Azide
Label: Conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use.
Conjugation PE
Storage Condition Store the antibody in the dark at 2-8°C.
Do Not Freeze!.
Avoid prolonged exposure to light.
Gene Name CD24 molecule
Background CD24, also known as heat-stable antigen (HSA) or nectadorin, is a small mucin-like GPI-anchored extracellular membrane glycoprotein expressed on several cell types, including B cells. When B cells are activated and induced to further maturation, however, CD24 begins to disappear. CD24 seems to act as a gate-keeper for lipid rafts, thereby regulating the activity of integrins and other proteins such as the chemokine receptor CXCR4; it is also a ligand for P-selectin. CD24 triggering induces apoptosis of B cell precursors but not in mature resting B cells, where it instead inhibits their ability to proliferate in response to activation. CD24 expression is associated with invasiveness and poorer prognosis of carcinomas and is a marker of exosomes secreted into urine and amniotic fluid.
Synonyms X62 heat stable antigen, HSA
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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