CD36 Mouse Monoclonal Antibody [Clone ID: TR9]

Specifications

Product Data
Clone Name	TR9
Applications	FC
Recommend Dilution	Flow Cytometry: 2 µg/ml.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Platelets.
Specificity	The antibody TR9 reacts with CD36 (GPIIIb), a 85 kDa integral membrane glycoprotein expressed on platelets, macrophages, endothelial cells, early erythroid cells and megakaryocytes. This antibody cross-blocks binding of FITC-labeled standard antibody OKM5. Anti-CD36 antibodies inhibit adhesive functions (e.g. adherence of infected erythrocytes to target cells).
Formulation	Tris Buffered Saline (TBS), pH~8.0 State: Purified State: Liquid purified Ig fraction from Ascites (> 95% pure by SDS-PAGE) Preservative: 15 mM Sodium Azide
Concentration	lot specific
Purification	Purified by protein-A affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C. DO NOT FREEZE!
Gene Name	CD36 molecule
Database Link	Entrez Gene 948 Human UniProt ID P16671
Background	CD36 (fatty acid translocase, FAT) is an 88 kDa ditopic glycosylated protein that belongs to the class B family of scavenger receptors. CD36 is expressed by most resting marginal zone B cells but not by follicular and B1 B cells, and it is rapidly induced on Follicular B cells in vitro upon TLR and CD40 stimulation. CD36 does not affect the development of B cells, but modulates both primary and secondary antibody response. Similarly to glucose transporter GLUT4, CD36 is translocated from intracellular pools to the plasma membrane following cell stimulation by insulin. In mouse, CD36 is responsible for gustatory perception of long-chain fatty acids.
Synonyms	Glycoprotein IIIb, PAS IV, PAS-4, Thrombospondin receptor, GP3B, GP4
Reference Data

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