C Reactive Protein (CRP) Mouse Monoclonal Antibody [Clone ID: C7]

Specifications

Product Data
Clone Name	C7
Applications	ELISA
Recommend Dilution	ELISA: The clone C7 has been tested as the detection antibody in a Sandwich ELISA for analysis of C-Reactive Protein in combination with the antibody clone C5 (Cat.-No. AM20202PU-N).
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified Human CRP
Specificity	The antibody C7 recognizes CRP, an 117 kDa acute phase protein. It recognizes antigen both in the presence and in the absence (samples containing EDTA) of Ca2+.
Formulation	Phosphate buffered saline (PBS), pH~7.4 State: Aff - Purified State: Liquid purified Ig fraction from Ascites (> 95% pure by SDS-PAGE) Preservative: 15 mM Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C. DO NOT FREEZE!
Gene Name	C-reactive protein, pentraxin-related
Database Link	Entrez Gene 1401 Human UniProt ID P02741
Background	The C-reactive protein (CRP) is a cyclic pentameric pentraxin family acute phase protein compound of five identical noncovalently bound nonglycosylated subunits (each subunit 24 kDa; physiologic CRP molecule 117,5 kDa). CRP is produced by the liver and its plasma levels rise dramatically during inflammatory processes occuring in the body. CRP is an initiator of classical complement cascade, binds to several nuclear components (chromatin, histones, etc.) and is also believed to play an important role in innate immunity. Patients with elevated basal levels of CRP are at increased risk for hypertension and cardiovascular disease.
Synonyms	PTX1, C Reactive Protein, Pentraxin-related
Reference Data

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