Cyclophilin B (PPIB) (26-216) Mouse Monoclonal Antibody [Clone ID: k2E2]

Specifications

Product Data
Clone Name	k2E2
Applications	ELISA, WB
Recommend Dilution	ELISA. Western blot: 1/1,000-1/2,000 (recommended starting dilution is 1/1,000).
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant Human Cyclophilin B (26-216aa) purified from E. coli
Specificity	This antibody detects Cyclophilin B.
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	peptidylprolyl isomerase B
Database Link	Entrez Gene 5479 Human UniProt ID P23284
Background	Cyclophilin B (also known as PPIB, peptidylpropyl isomerase B) is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Cyclophilin B is necessary for the prolactin-induced proliferation, cell growth, and the nuclear retrotransport of prolactin.
Synonyms	PPIase B, Rotamase B, S-cyclophilin, CYP-S1, PPIB, CYPB, SCYLP
Reference Data

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