Cd86 Rat Monoclonal Antibody [Clone ID: PO3]

CAT#: AM05571RP-N

Cd86 rat monoclonal antibody, clone PO3, PE

Conjugation: FITC PE



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CNY 6,369.00


货期*
4周

规格
    • 100 Tests

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Specifications

Product Data
Clone Name PO3
Applications FC
Recommend Dilution Flow Cytometry: 1/10.
Reactivity Mouse
Host Rat
Clonality Monoclonal
Immunogen Mouse B-cell line, BCL1.
Specificity This antibody recognises CD86 (B7-2). The PO3 clone has been reported to block some co-stimulatory functions of CD86.
Formulation Phosphate buffered saline pH7.4 containing 0.09% Sodium Azide, 1% Bovine Serum Albumin
Label: PE
State: Lyophilised purified IgG
Label: R. Phycoerythrin (RPE)
Reconstitution Method Reconstitute with 1.0 ml distilled water
Concentration lot specific
Purification Affinity chromatography on Protein G
Conjugation PE
Storage Condition Prior to and following reconstitution store the antibody at 2-8°C.
DO NOT FREEZE!
This product is photosensitive and should be protected from light.
Gene Name CD86 antigen
Background CD86 is an 80kD cell surface glycoprotein which is a member of the CD28/B7 family. In mouse, CD86 is expressed at high levels on peripheral blood monocytes, dendritic cells and at low levels on resting B and T-lymphocytes. Expression of CD86 on these cell populations can be increased upon activation. CD86 has been identified, along with CD80 (B7-1) as a ligand for CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA4). CD28 and CTLA4 are two receptors that have opposing functions in T-cell stimulation. Interaction of CD86 with CD28 promotes a number of T-cell activities, whereas the binding of CD86 to CTLA4 inhibits T-cell responses.
Synonyms CD28LG2, Activation B7-2 antigen, B70, BU63, B7.2, FUN-1
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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