MHC Class II Mouse Monoclonal Antibody [Clone ID: PF6J-6D]

Specifications

Product Data
Clone Name	PF6J-6D
Applications	ELISA, FC, WB
Recommend Dilution	ELISA: Can be used in ELISA in conjunction with AM05897PU-N (clone PF8J-9B). Western blot: Detects band/s of approximately 29-31kDa on fractionated Cat lymphocyte cell lysates under non-reducing conditions. Flow Cytometry.
Reactivity	Feline
Host	Mouse
Clonality	Monoclonal
Specificity	This antibody specifically recognises an epitope within the 29-31kDa beta chain region of cat MHC class II.
Formulation	Phosphate buffered saline pH 7.2 State: Purified State: Liquid purified Ig fraction Preservative: 0.05% Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Background	The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In cats, this is referred to as the feline leukocyte antigen (FLA) region. The complex retrovirus FIV (feline immunodeficiency virus), is responsible for a progressive and debilitating immune deficiency syndrome in domestic cats, similar to that caused by the human Immunodeficiency virus (HIV). Studies have shown that the intensity of MHC Class II expression on cat lymphocyte membranes has been found to vary in association with feline retrovirus infections.
Synonyms	MHC Class 2, HLA Class II
Reference Data

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