AKT3 (119-136) Mouse Monoclonal Antibody [Clone ID: 66C1247.1]

CAT#: AM06001PU-N

AKT3 (119-136) mouse monoclonal antibody, clone 66C1247.1, Purified



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CNY 5,654.00


货期*
6周

规格
    • 50 ug

Product images

Specifications

Product Data
Clone Name 66C1247.1
Applications IHC, WB
Recommend Dilution Immunohistochemistry on Paraffin Sections: 10 µg/ml.
Western Blot: 1 - 2 µg/ml.
Reactivity Human, Mouse, Rat, Bovine, Bat, Canine, Chicken, Equine, Monkey, Porcine, Rabbit
Host Mouse
Clonality Monoclonal
Immunogen Synthetic peptide corresponding to amino acid residues 119-136 of Human Akt3
Specificity This antibody detects V-Akt Murine Thymoma Viral Oncogene Homolog 3 (AKT3) at aa 119-136.
Family: Protein Kinase
Subfamily: RAC/AKT
Formulation PBS, 0.05% BSA, 0.05% sodium azide. Sourced in TCS
State: Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Protein G Chromatography
Conjugation Unconjugated
Storage Condition

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Gene Name AKT serine/threonine kinase 3
Background Akt, protein kinase B (PKB), is a serine/threonine kinase which is involved in many cellular signaling pathways and acts as a transducer of many functions initiated by growth factor receptors that activat phosphtidylinositol 3-kinase (PI 3-kinase). The major activity of Akt/PKB is to mediate cell survival. Akt/PKB is also believed to be a critical factor in the genesis of cancer as the tumor suppressor PTEN was found to antagonise PI-3 kinase and Akt/PKB kinase activity. There are 3 known isoforms of this enzyme in mammalian cells (1/alpha, 2/beta and 3/gamma). Akt1, 2 and 3 contain a key regulatory serine phosphorylation site in the carboxy-terminal region of the protein. Akt/PKB phosphorylation is critical for it activity.
Synonyms RAC-PK-gamma, Protein kinase B gamma, PKBG, STK-2
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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