ATRX (C-term) Mouse Monoclonal Antibody [Clone ID: 60.1]

Specifications

Product Data
Clone Name	60.1
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA. Immunohistochemistry on Paraffin Sections: 5 µg/ml. Western Blot.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Synthetic peptide from Human ATRX.  RAD54L antibody was raised against combination of N & C peptide, corresponding to a range between amino acids 1-300 and 450-741. Epitope: C-Terminus.
Specificity	Peptides from N and C termini of RAD54L (ATRX). This antibody detetcs X-Linked Helicase II (ATRX).
Formulation	PBS, pH 7.2 State: Purified State: Liquid purified Ig fraction Preservative: None
Concentration	lot specific
Purification	Protein G Chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	ATRX, chromatin remodeler
Database Link	Entrez Gene 546 Human UniProt ID P46100
Background	The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination.
Synonyms	RAD54L, XNP, Znf-HX
Reference Data

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