Nucleophosmin (NPM1) Mouse Monoclonal Antibody [Clone ID: 7H10B9]
CAT#: AM06071SU-N
Nucleophosmin (NPM1) mouse monoclonal antibody, clone 7H10B9, Ascites
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CNY 4,536.00
货期*
5周
规格
Specifications
Product Data | |
Clone Name | 7H10B9 |
Applications | IF, IHC, WB |
Recommend Dilution | ELISA: 1/10000. Western Blot: 1/500-1/2000. Immunofluorescence: 1/200-1/1000. Immunohistochemistry on Paraffin Sections: 1/200-1/1000. |
Reactivity | Human, Monkey |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Purified recombinant fragment of Human NPM expressed in E. Coli. |
Specificity | This antibody recognizes Human Nucleophosmin. Other species not tested. |
Formulation | State: Ascites State: Ascitic fluid Preservative: 0.03% Sodium Azide |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Gene Name | nucleophosmin (nucleolar phosphoprotein B23, numatrin) |
Database Link | |
Background | Nucleophosmin (NPM), also named B23 or NO38, is a major nucleolar protein which is 20 times more abundant in tumor or proliferating cells than in normal resting cells. NPM has been implicated in several distinct cellular functions, including assembly and transport of ribosomes, cytoplasmic/nuclear trafficking, regulation of DNA polymerase alpha activity, centrosome duplication and molecular chaperoning activities. The NPM is also known for its fusion with the anaplastic lymphoma kinase (ALK) receptor tyrosine kinase. The NPM portion contributes to transformation by providing a dimerization domain, which results in activation of the fused kinase. |
Synonyms | NPM, NPM1, Numatrin |
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