CIB1 Mouse Monoclonal Antibody [Clone ID: 5A1F5E12]
CAT#: AM06136SU-N
CIB1 mouse monoclonal antibody, clone 5A1F5E12, Ascites
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CNY 5,346.00
货期*
5周
规格
Specifications
Product Data | |
Clone Name | 5A1F5E12 |
Applications | ELISA, IHC, WB |
Recommend Dilution | ELISA: 1/10000. Western Blot: 1/500 - 1/2000. Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Purified recombinant fragment of CIB1 expressed in E. Coli. |
Formulation | State: Ascites State: Ascitic fluid Preservative: 0.03% Sodium Azide |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Gene Name | calcium and integrin binding 1 |
Database Link | |
Background | CIB1 (also designated calcium and integrin binding 1 or calmyrin),with 191-amino acid protein(about 21kDa), belongs to the calcium-binding protein family.CIB1 is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining.CIB1 is an EF-hand-containing protein that binds multiple effector proteins, including the platelet alpha(IIb)beta(3) integrin and several serine/threonine kinases and potentially modulates their function.CIB1 regulates platelet aggregation in hemostasis through a specific interaction with the alpha(IIb) cytoplasmic domain of platelet integrin alpha(IIb)beta(3). CIB1 is also ubiquitously expressed activating and inhibiting protein ligand of the InsP3R. |
Synonyms | Calmyrin, KIP, PRKDCIP, SIP2-28, CIBP |
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