LPP Mouse Monoclonal Antibody [Clone ID: 8B3A11]

Specifications

Product Data
Clone Name	8B3A11
Applications	IF, IHC, WB
Recommend Dilution	ELISA: 1/10000. Western Blotting: 1/500-1/2000. Immunofluorescence: 1/200-1/1000. Immunohistochemistry on Paraffin Sections: 1/200-1/1000.
Reactivity	Hamster, Human, Monkey, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of Human LPP expressed in E. Coli.
Specificity	Recognizes LIM Protein / LPP.
Formulation	State: Ascites State: Ascitic fluid Preservative: 0.03% Sodium Azide
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	66 kDa
Gene Name	LIM domain containing preferred translocation partner in lipoma
Database Link	Entrez Gene 4026 Human UniProt ID Q93052
Background	LIM domain containing preferred translocation partner in lipoma. The Zyxin family of proteins contains five members, Ajuba, LIMD1, LPP,TRIP6 and Zyxin. LPP (LIM-containing lipoma-preferred partner), a LIM domain-containing scaffolding protein contains three LIM domains at its carboxyterminus, which are preceded by a proline-rich pre-LIM region containing a number of protein interaction domains. LPP, an 80 kDa protein, localizes to sites of cell adhesion, such as focal adhesions and cell-cell contacts,and shuttles to the nucleus where it has transcriptional activation capacity.The human LPP gene maps to chromosomal location 3q28, and preferentiallytranslocates to the HMGIC gene in a subclass of human benign mesenchymal tumors known as lipomas.
Synonyms	LPP, Lipoma-preferred partner
Reference Data

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