IGFBP2 Mouse Monoclonal Antibody [Clone ID: 1F6F6]

Specifications

Product Data
Clone Name	1F6F6
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA: 1/10000. Western Blot: 1/500 - 1/2000. Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of protein IGFBP2 (aa180-328) expressed in E. Coli.
Specificity	Recognizes Insulin-like growth factor binding protein 2 (IGFBP2)
Formulation	State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	insulin like growth factor binding protein 2
Database Link	Entrez Gene 3485 Human UniProt ID P18065
Background	Insulin-like growth factor binding protein 2 (IGFBP2) is a member of the ISGBP family which bind various IGFs. IGFBP2 is overexpressed in a wide spectrum of other cancers, including glioma, prostate cancer, synovial sarcoma, neuroblastoma, colon cancer, adrenocortical cancer, lung cancer, Wilms' tumor, and hepatoblastoma. The overexpression of IGFBP2 also correlates with the aggressiveness of some tumors. IGFBP2 activates the expression of matrix metalloprotease 2, which contributes to cell invasiveness.
Synonyms	IGF-binding protein 2, IGFBP-2, IBP2, IBP-2
Reference Data

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