AXL Mouse Monoclonal Antibody [Clone ID: 7E10]

Specifications

Product Data
Clone Name	7E10
Applications	ELISA, IF, WB
Recommend Dilution	ELISA: 1/10000. Western Blot: 1/500-1/2000. Immunofluorescence: 1/200-1/1000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant extracellular fragment of Human AXL fused with hIgGFc tag expressed in HEK293 cell line.
Specificity	Recognizes AXL receptor tyrosine kinase
Formulation	State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	97.4 kDa
Gene Name	AXL receptor tyrosine kinase
Database Link	Entrez Gene 558 Human UniProt ID P30530
Background	AXL receptor tyrosine kinase, also known as UFO, JTK11 is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.
Synonyms	JTK11; UFO
Reference Data

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