Superoxide Dismutase 1 (SOD1) Mouse Monoclonal Antibody [Clone ID: 6F5]

Specifications

Product Data
Clone Name	6F5
Applications	ELISA, IF, WB
Recommend Dilution	ELISA: 1/10,000. Western Blot: 1/500 - 1/2000. Flow Cytometry: 1/200 - 1/400. Immunocytochemistry: 1/200 - 1/1000.
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of human SOD1 expressed in E. Coli.
Specificity	Recognizes SOD1 (superoxide dismutase 1, soluble).
Formulation	State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	18 kDa
Gene Name	superoxide dismutase 1, soluble
Database Link	Entrez Gene 6647 Human UniProt ID P00441
Background	SOD1 (superoxide dismutase 1, soluble), also known as ALS. The protein binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis (ALS), a progressive degenerative disease of motor neurons. Rare transcript variants have been reported for this gene.
Synonyms	SOD-1, CuZn-SOD, CuZnSOD, IPOA, ALS1
Reference Data

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