RAG2 Mouse Monoclonal Antibody [Clone ID: 4D5]

CAT#: AM06429SU-N

RAG2 mouse monoclonal antibody, clone 4D5, Ascites



Need it in bulk or conjugated?
Get a free quote

CNY 4,536.00


货期*
5周

规格
    • 100 ul

Product images

Specifications

Product Data
Clone Name 4D5
Applications ELISA, WB
Recommend Dilution Western Blot: 1/500 - 1/2000.
ELISA: 1/10000.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Purified recombinant fragment of human RAG2(350-527aa) expressed in E. Coli.
Specificity This antibody reacts to RAG2.
Formulation State: Ascites
State: Ascitic fluid containing 0.03% sodium azide.
Conjugation Unconjugated
Storage Condition

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Predicted Protein Size 59 kDa
Gene Name recombination activating gene 2
Background This gene encodes a protein that is involved in the initiation of V(D)J recombination during B and T cell development. This protein forms a complex with the product of the adjacent recombination activating gene 1, and this complex can form double-strand breaks by cleaving DNA at conserved recombination signal sequences. The recombination activating gene 1 component is thought to contain most of the catalytic activity, while the N-terminal of the recombination activating gene 2 component is thought to form a six-bladed propeller in the active core that serves as a binding scaffold for the tight association of the complex with DNA. A C-terminal plant homeodomain finger-like motif in this protein is necessary for interactions with chromatin components, specifically with histone H3 that is trimethylated at lysine 4. Mutations in this gene cause Omenn syndrome, a form of severe combined immunodeficiency associated with autoimmune-like symptoms.
Synonyms RAG-2
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
Customer Reviews 
Loading...