SMAD4 Mouse Monoclonal Antibody [Clone ID: 4G1C6]
CAT#: AM06501SU-N
SMAD4 mouse monoclonal antibody, clone 4G1C6, Ascites
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CNY 5,346.00
货期*
5周
规格
Specifications
Product Data | |
Clone Name | 4G1C6 |
Applications | ELISA, FC, IF, IHC, WB |
Recommend Dilution | ELISA: 1/10000. Western Blot: 1/500 - 1/2000. Flow Cytometry: 1/200 - 1/400. Immunofluorescence: 1/200 - 1/1000. Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Purified recombinant fragment of Human SMAD4 expressed in E. Coli. |
Specificity | Recognizes SMAD4 |
Formulation | State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide. |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Predicted Protein Size | 65 kDa |
Gene Name | SMAD family member 4 |
Database Link | |
Background | Common mediator of signal transduction by TGF-beta (transforming growth factor) superfamily; SMAD4 is the common SMAD (co-SMAD). Promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. May act as a tumor suppressor。Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome. |
Synonyms | SMAD family member 4, SMAD-4, SMAD 4, MADH4, MAD homolog 4, DPC4 |
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