AKT1 Mouse Monoclonal Antibody [Clone ID: 3A3]

CAT#: AM06526SU-N

AKT1 mouse monoclonal antibody, clone 3A3, Ascites



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CNY 5,346.00


货期*
5周

规格
    • 100 ul

Product images

Specifications

Product Data
Clone Name 3A3
Applications ELISA, WB
Recommend Dilution Western Blot: 1/500 - 1/2000.
ELISA: 1/10000.
Reactivity Human, Monkey, Mouse
Host Mouse
Clonality Monoclonal
Immunogen Purified recombinant fragment of human AKT1 expressed in E. Coli.

Specificity This antibody reacts to AKT1.
Formulation State: Ascites
State: Ascitic fluid containing 0.03% sodium azide.
Conjugation Unconjugated
Storage Condition

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Predicted Protein Size 56 kDa
Gene Name AKT serine/threonine kinase 1
Background The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Multiple alternatively spliced transcript variants have been found for this gene.
Synonyms Akt-1, RAC-PK-alpha, Protein kinase B, C-AKT
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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