p57 Kip2 (CDKN1C) Mouse Monoclonal Antibody [Clone ID: 3E3]

Specifications

Product Data
Clone Name	3E3
Applications	ELISA, WB
Recommend Dilution	ELISA: 1/10000. Western Blot: 1/500 - 1/2000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of Human CDKN1C expressed in E. Coli.
Specificity	Recognizes CDKN1C / KIP2
Formulation	State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	57 kDa
Gene Name	cyclin-dependent kinase inhibitor 1C
Database Link	Entrez Gene 1028 Human UniProt ID P49918
Background	The protein encoded by this gene is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.Tissue specificity: Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. High levels are seen in the placenta while low levels are seen in the liver.
Synonyms	p57KIP2
Reference Data

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