RUNX1 Mouse Monoclonal Antibody [Clone ID: 2B5]

Specifications

Product Data
Clone Name	2B5
Applications	ELISA, WB
Recommend Dilution	ELISA: 1/10000. Western Blot: 1/500 - 1/2000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Synthesized peptide of Human RUNX1.
Specificity	Recognizes
Formulation	State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	55 kDa
Gene Name	runt related transcription factor 1
Database Link	Entrez Gene 861 Human UniProt ID Q01196
Background	Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) Tissue specificity: Expressed in all tissues examined except brain and heart. Highest levels in thymus, bone marrow and peripheral blood.
Synonyms	Runt-related transcription factor, 1, AML1, AML-1, AMLCR1, Acute myeloid leukemia 1 protein, AML1-EVI-1, EVI-1, CBFA2, CBF-alpha-2, PEA2-alpha B, PEBP2-alpha B, PEBP2A2
Reference Data

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