Neurofilament (NEFL) Mouse Monoclonal Antibody [Clone ID: 2G10]

Specifications

Product Data
Clone Name	2G10
Applications	ELISA, FC, IF, IHC, WB
Recommend Dilution	Western Blot: 1/500 - 1/2000. Immunohistochemistry on paraffin sections: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of human NEFL expressed in E. Coli.
Specificity	This antibody reacts to NEFL.
Formulation	PBS State: Purified State: Liquid purified Ig fraction Stabilizer: 0,5% BSA Preservative: 0.05% sodium azide
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	62 kDa
Gene Name	neurofilament, light polypeptide
Database Link	Entrez Gene 4747 Human UniProt ID P07196
Background	Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.
Synonyms	NF-L,NEFL, NF68, 68 kDa neurofilament protein
Reference Data

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