Cd22 Rat Monoclonal Antibody [Clone ID: 2D6]
CAT#: AM08033AC-N
Cd22 rat monoclonal antibody, clone 2D6, APC
Conjugation: Unconjugated Biotin FITC PE
Need it in bulk or conjugated?
Get a free quote
CNY 4,576.00
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
Specifications
Product Data | |
Clone Name | 2D6 |
Applications | FC |
Recommend Dilution | Flow Cytometry: < / = 0.2 µg/10e6 cells. (Ref.2) |
Reactivity | Mouse |
Host | Rat |
Clonality | Monoclonal |
Specificity | This antibody is specific to CD22 (Mr 150 kDa), a B Lymphocyte Adhesion Molecule. |
Formulation | PBS containing 0.09% Sodium Azide as preservative and a stabilizing agent. Label: APC State: Liquid purified Ig fraction. Label: Allophycocyanin |
Concentration | lot specific |
Conjugation | APC |
Storage Condition | Store the antibody undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing. |
Gene Name | CD22 antigen |
Database Link | |
Background | CD22, also known as Lyb-8, is a heterodimeric transmembrane glycoprotein and a member of a structurally related group of immunoglobulin (Ig) superfamily domain-containing proteins called the sialoadhesin family. It is detected in the cytoplasm early in B cell development (late pro-B cell stage), appears on the cell surface concomitant with IgD, and is found on most IgM+IgD+ mature B lymphocytes. Expression is lost with terminal differentiation of B cells and is absent on plasma cells. Activation of B cells via cross-linking of surface Ig increases CD22 expression. (Ref.1,2) CD22 associates with the B cell receptor (BCR) complex and mediates intercellular adhesion. (Ref.2-4) Its intracellular domain is phosphorylated after antigen receptor crosslinking and is involved in negative regulation of B-cell activation. (Ref.6-9) |
Synonyms | SIGLEC2, Siglec-2, B-cell receptor CD22, Leu-14, BL-CAM |
Reference Data |
Documents
Product Manuals |
FAQs |
SDS |
Resources
抗体相关资料 |