Enpep Rat Monoclonal Antibody [Clone ID: FG35.4]

Specifications

Product Data
Clone Name	FG35.4
Applications	FC
Recommend Dilution	Flow Cytometry: < / = 1 µg/10e6 cells. (Ref.12)
Reactivity	Mouse
Host	Rat
Clonality	Monoclonal
Specificity	This antibody is specific to BP1 (Ly-51/6C3).
Formulation	PBS containing 0.09% Sodium Azide as preservative. Label: FITC State: Liquid purified Ig fraction. Label: Fluorescein Isothiocyanate Isomer 1
Concentration	lot specific
Conjugation	FITC
Storage Condition	Store the antibody undiluted at 2-8°C for one month or in (aliquots) at -20°C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Gene Name	glutamyl aminopeptidase
Database Link	Entrez Gene 13809 Mouse UniProt ID P16406
Background	BP1, also known as Ly51/6C3 antigen, is a type II homodimeric transmembrane glycoprotein formed by two disulfide-linked chains of 140 kDa. (Ref.1,2) Originally identified on the surface of pre-B cell lymphomas (Ref.1,3) the cDNA encoding BP1 has been cloned and found to represent Aminopeptidase A. (Ref.4,5) It is expressed at high levels on bone marrow stromal cell lines which support in vitro B lymphopoiesis and on a wide variety of Mouse tissues known to possess aminopeptidase activity. (Ref.6-8) Subsets of normal bone marrow pre-B and B cells express low levels of BP1, which is rapidly upregulated on pre-B cells in the presence of IL-7. (Ref.9,10) The BP1 marker is commonly used to identify B cells in different stages of development. (Ref.11)
Synonyms	EAP, Aminopeptidase A, ENPEP
Reference Data

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