Ctla4 Hamster Monoclonal Antibody [Clone ID: 1B8]

Specifications

Product Data
Clone Name	1B8
Applications	FC
Recommend Dilution	Flow Cytometry: < / = 3 µg/10e6 cells. (Ref.1,2)
Reactivity	Mouse
Host	Hamster
Clonality	Monoclonal
Specificity	This Monoclonal antibody is specific to CD152/CTLA-4.
Formulation	PBS containing 0.09% Sodium Azide as preservative. Label: FITC State: Liquid purified Ig fraction. Label: Fluorescein Isothiocyanate Isomer 1
Concentration	lot specific
Conjugation	FITC
Storage Condition	Store the antibody undiluted at 2-8°C for one month or in (aliquots) at -20°C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Gene Name	cytotoxic T-lymphocyte-associated protein 4
Database Link	Entrez Gene 12477 Mouse UniProt ID P09793
Background	The lymphocyte surface antigen CD152, also known as CTLA-4, is related to the co-stimulatory molecule CD28, and both molecules share common B7 family counter-receptors. (Ref.1-4) However CD152 is thought to be a negative regulator of T cell activation (Ref.1-3) and may play a role in apoptotic control of T cells. CD152 exists as a 69 kDa homodimer (Ref.1), and is relatively conserved among Humans, Mice and Chickens. (Ref.2)
Synonyms	CTLA-4
Reference Data

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