Cd79b Hamster Monoclonal Antibody [Clone ID: HM79-12]

Specifications

Product Data
Clone Name	HM79-12
Applications	FC, IHC, IP, WB
Recommend Dilution	Flow Cytometry. (Ref.1,2) Immunoprecipitation. (Ref.1) Immunohistochemistry on Frozen Sections. (Ref.3) Western Blotting. (Ref.1)
Reactivity	Mouse
Host	Hamster
Clonality	Monoclonal
Specificity	This antibody recognises beta chain of the mouse B-cell receptor (Mr. 23 kDa).
Formulation	PBS without preservatives. State: Low Endotoxin State: Liquid purified Ig fraction.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	CD79B antigen
Database Link	Entrez Gene 15985 Mouse UniProt ID P15530
Background	Murine CD79 is a 23/21 kDa disulfide-linked heterodimer composed of an alpha chain (CD79a/mb-1) and a beta chain (CD79b/B29) that associates non-covalently with membrane immunoglobulin (Ig) to form the B cell receptor (BCR) complex. Its expression is restricted to B lymphocytes, first appearing on the surface at the pro-B cell stage prior to productive Ig gene rearrangements and remaining through all stages of B-cell differentiation prior to plasma cells. It has been proposed that the CD79 complex on pro-B cell surfaces may function to induce early B-cell differentiation. (Ref.1)
Synonyms	B29, IGB, B-Cell marker
Reference Data

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