MHC Class II I-Ab Rat Monoclonal Antibody [Clone ID: NIMR-4]

CAT#: AM08075RP-S

MHC Class II I-Ab rat monoclonal antibody, clone NIMR-4, PE

Size: 100 ug 200 ug



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CNY 4,169.00


货期*
4周

规格
    • 100 ug

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Specifications

Product Data
Clone Name NIMR-4
Applications FC
Recommend Dilution Flow Cytometry: < / = 0.1 µg/10e6 cells.
Reactivity Mouse
Host Rat
Clonality Monoclonal
Specificity Specific to MHC Class II molecules.
This antibody reacts specifically with a non-polymorphic I-A-encoded epitope on MHC Class II antigens. Class II antigens are predominantly expressed on antigen-presenting cells including B lymphocytes, macrophages, dendritic cells and certain epithelial cells.
Formulation PBS containing 0.09% Sodium Azide as preservative and a stabilizing agent.
Label: PE
State: Liquid purified Ig fraction.
Label: R-Phycoerythrin
Concentration lot specific
Conjugation PE
Storage Condition Store the antibody undiluted at 2-8°C.
DO NOT FREEZE!
This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing.
Background MHC Class II antigens are heterodimers consisting of one alpha chain(31-34kD) and one beta chain (26-29kD). The family of monoclonal antibodies (ER-TR 3, ER-TR 2, ER-TR 1) detect MHC class II antigens encoded by the murine Ia region of the H-2 complex, corresponding to the human HLA-DR region. MHC Class II antigens are a valuable tool for studying T helper cell interaction with class II positive antigen presenting cells (dendritic cells, B cells, macrophages) and offer new possibilities for studying the development of T helper cells since these antibodies also stain stromal cells in the thymus. MHC Class II antigens are also inducible on a number of other cells (endothelium and epithelial cells) by interferon gamma.
Synonyms H2-Eb1, H-2 class II histocompatibility antigen I-A beta chain
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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