Lamp2 Rat Monoclonal Antibody [Clone ID: ABL-93]

Specifications

Product Data
Clone Name	ABL-93
Applications	FC, IHC, IP
Recommend Dilution	Flow Cytometry: < / = 1 µg/10e6 cells. Immunohistochemistry (Acetone-Fixed, Frozen Tissue Sections only). (Ref.2,5) Immunoprecipitation. (Ref.2)
Reactivity	Mouse
Host	Rat
Clonality	Monoclonal
Immunogen	Glycoproteins purified from BALB/c mouse embryo 3T3 cell line. (Ref.1)
Specificity	This antibody is specific to CD107b/LAMP-2 (Mr 110-120 kDa with a core protein of Mr ~40 kDa).
Formulation	100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	lysosomal-associated membrane protein 2
Database Link	Entrez Gene 16784 Mouse UniProt ID P17047
Background	CD107b, also known as lysosomal-associated membrane protein 2 (LAMP-2), is a heavily glycosylated, type I transmembrane protein that constitutes one of the two major sialoglycoproteins on lysosomal membranes that can be used to distinguish lysosomes from other organelles. (Ref.1) CD107b is similar in structure to Mac-1 and is expressed primarily on epithelial cells and macrophages in a variety of organs in normal and Beige mutant mice. (Ref.2)
Synonyms	LAMP-2, LAMP-2C, LAMPB
Reference Data

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