Cytokeratin 18 (KRT18) (N-term) Mouse Monoclonal Antibody [Clone ID: SB38b]
CAT#: AM08175PU-N
Cytokeratin 18 (KRT18) (N-term) mouse monoclonal antibody, clone SB38b, Purified
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CNY 4,026.00
货期*
4周
规格
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Specifications
Product Data | |
Clone Name | SB38b |
Applications | ELISA, IHC, WB |
Recommend Dilution | ELISA: 1/5,000-1/20,000. Western Blot: 1/2,000-1/4,000. Immunohistochemistry (Acetone-Fixed, Frozen Tissue Sections): 10 µg/ml |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Recombinant N-terminal fragment of keratin 18. |
Specificity | This antibody reacts specifically specifically with Keratin 18 and recombinant N-terminal Keratin 18. |
Formulation | 100 mM Borate buffered saline, pH 8.0 without preservatives or amine-containing buffer salts. State: Purified State: Liquid purified Ig fraction. |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2-8°C. |
Gene Name | keratin 18 |
Database Link | |
Background | Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1-8). The two keratin types share only 30% sequence homology. (Ref.1-6) Keratins demonstrate tissue- and differentiation-specific expression profiles. Cytokeratin 18, also known as keratin 18, is a type I intermediate filament protein of approximately 48 kDa. It exists as a heterotetramer composed of two type I and two type II keratins. Cytokeratin 18 is expressed in all simple type epithelia and basal cells of many squamous and non-epidermal epithelia, and is often co-expressed with cytokeratin 8. (Ref.6-8) Tissues from the gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18. |
Synonyms | Cytokeratin-18, CK18, Keratin-18, Keratin 18, KRT18, CYK18, K18 |
Note | Chatacterization: To ensure acceptable performance, each batch of product is tested by ELISA, Immunohistochemical staining (HT29 and HCC38 cells) and Western blotting (HT29 and HCC38 cell lysates) to conform to characteristics of a standard reference reagent. |
Reference Data |
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