TLR8 (750-850) Mouse Monoclonal Antibody [Clone ID: 44C143]

Specifications

Product Data
Clone Name	44C143
Applications	FC, IHC, WB
Recommend Dilution	Flow Cytometry. Immunohistochemistry on Paraffin Sections: 5 µg/ml. Western Blot: 1 - 3 µg/ml.
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	A KLH-conjugated synthetic peptide corresponding to a region within amino acids 750-850 of Human TLR8.
Specificity	The antibody recognizes Toll-like receptor 8 at aa 750-850.
Formulation	PBS State: Purified State: Liquid purified Ig fraction Preservative: 0.05% Sodium Azide
Concentration	lot specific
Purification	Protein G Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	toll like receptor 8
Database Link	Entrez Gene 51311 Human UniProt ID Q9NR97
Background	The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules (1). The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition (2). Ten human homologs of TLRs (TLR1-10) have been described (3). TLR8 gene contains three exons, two of which have coding function (4). TLR8 cDNA codes for a protein of approximate molecular weight of 120 kDa (4,5).
Synonyms	Toll-like receptor 8, UNQ249/PRO286
Reference Data

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