PGP9.5 (UCHL1) Mouse Monoclonal Antibody [Clone ID: 3D9]

Specifications

Product Data
Clone Name	3D9
Applications	ELISA, IF, IHC, WB
Recommend Dilution	ELISA. Western blot: 1/1,000-1/2,000. Flow Cytometry. Immunofluorescence/Immnunocytochemistry. Immunohistochemistry on Paraffin Sections: 1/100-1/200.
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human PGP9.5 (1-223 aa) purified from E. coli
Specificity	The antibody recognizes Human and Mouse PGP9.5. Other species not tested.
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	ubiquitin C-terminal hydrolase L1
Database Link	Entrez Gene 7345 Human UniProt ID P09936
Background	PGP9.5/UCH-L1 is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. PGP9.5 is a component of the ubiquitin system, which has a fundamental role in regulating various biological activities. PGP9.5 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility.
Synonyms	UCH-L1, PGP 9.5, Ubiquitin thioesterase L1, Neuron cytoplasmic protein 9.5
Reference Data

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