TOLLIP Mouse Monoclonal Antibody [Clone ID: k1B17]

Specifications

Product Data
Clone Name	k1B17
Applications	ELISA, IF, WB
Recommend Dilution	ELISA. Western blot (1/500-1/1,000). Immunofluorescence.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human Tollip (61-274 aa) purified from E. coli
Specificity	The antibody recognizes human TOLLIP. Other species not tested.
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	toll interacting protein
Database Link	Entrez Gene 54472 Human UniProt ID Q9H0E2
Background	Toll interacting protein, also known as Tollip, is an inhibitory adaptor protein within the signaling pathway of IL-1 and Toll-like receptors(TLR). The Toll-like receptors are essential transmembrane signaling receptors of the innate immune system that alert the host to the presence of a microbial invader. Tollip recruits IRAK1 to the IL-1 receptor complex and inhibits IRAK1 phosphorylation and kinase activity.
Synonyms	Toll-interacting protein
Reference Data

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