MAT2A Mouse Monoclonal Antibody [Clone ID: AT3A2]

Specifications

Product Data
Clone Name	AT3A2
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA. Western blot (1:1,000 - 1:2,000)). Immunohistochemistry on Paraffin embedded tissues (1:50 - 1:100).
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human MAT2A (1-395 aa) purified from E. coli
Specificity	The antibody recognizes human MAT2A. Other species not tested.
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	methionine adenosyltransferase 2A
Database Link	Entrez Gene 4144 Human UniProt ID P31153
Background	Methionine adenosyltransferase II (MAT II) is a key enzyme in cellular metabolism and catalyzes the formation of S-adenosylmethionine (SAMe) from L-methionine and ATP. MAT2A is expressed in extrahepatic tissues. In liver, MAT2A expression associates with growth, dedifferentiation, and cancer.
Synonyms	S-adenosylmethionine synthetase isoform type-2, AdoMet synthetase 2, AMS2, MATA2
Reference Data
Protein Pathways	Cysteine and methionine metabolism, Metabolic pathways, Selenoamino acid metabolism

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