LANA ORF73 (122-329) Mouse Monoclonal Antibody [Clone ID: AT4C11]

Specifications

Product Data
Clone Name	AT4C11
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA. Western blot (1/1000-1/2000). Immunohistochemistry on Paraffin Embedded Sections (1/50-1/100).
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant Human ORF73/HHV8 (122-329 aa) purified from E. coli
Specificity	The antibody recognizes the ORF73 protein of Human herpesvirus 8 (HHV-8). Other species not tested.
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Database Link	Entrez Gene 4961527 UniProt ID Q9QR71
Background	ORF73 protein of human herpesvirus 8 (HHV-8) is a Kaposi's sarcoma-associated herpesvirus (KSHV) latent protein which has been suspected of playing a crucial role in modulating viral and cellular gene expression. ORF73 is associated with cellular chromatin and stays on the chromosomes during cell division. It maintains the viral genomes during cell division by tethering the viral episomes to the chromosomes. It binds directly to replication origin recognition complexes (ORCs) that are primarily associated with the terminal repeat (TR) region of the HHV-8 genome.
Synonyms	ORF-73, HHV-8, LANA-1, LNA, LNA1
Reference Data

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