Cytokeratin 18 (KRT18) (Multi-Epitope Cocktail) Mouse Monoclonal Antibody [Clone ID: Ks18.04/18.27/18.5/9B1/18.174]
CAT#: AM09125SU-N
Cytokeratin 18 (KRT18) (Multi-Epitope Cocktail) mouse monoclonal antibody, clone Ks18.04/18.27/18.5/9B1/18.174, Supernatant
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CNY 4,420.00
货期*
5周
规格
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Specifications
Product Data | |
Clone Name | Ks18.04/18.27/18.5/9B1/18.174 |
Applications | IHC, WB |
Recommend Dilution | Immunoblotting (Western). Immunohistochemistry on Frozen and paraffin-Embedded Tissue (only when using the microwave method) and Cytological Material. Working Dilution: Ready-to-use for Immunohistochemistry. Incubation Time: 1h at RT, extended with paraffin sections (over night at 2-8°C). |
Reactivity | Bovine, Canine, Fish, Hamster, Human, Mammalian, Mouse, Porcine, Rat, Sheep |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Keratin K18 of Human and Bovine origin. |
Specificity | The antibody cocktail represents an excellent marker to discriminate simple epithelia from those of different origin. Tumors Specifically Detected: all adenocarcinoma; mammary carcinoma, urinary bladder carcinoma, undifferentiated carcinoma, cervix carcinoma, hepatocellular carcinoma. Polypeptide Reacting: Mr 45 000 polypeptide (human and bovine K18; formerly also designated cytokeratin 18) of all simple type epithelia and basal cells of many squamous, nonepidermal epithelia. Reactivities on Cultured Cell Lines: HeLa and MCF-7. |
Formulation | State: Supernatant State: Hybridoma Culture Supernatant Preservative: 0.09% Sodium Azide |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2-8°C. |
Gene Name | keratin 18 |
Database Link | |
Background | Cytokeratin 18 is an acidic keratin which is found primarily in non-squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas but not in squamous cell carcinomas. Cytokeratin 18 exists in combination with Cytokeratin 8, a basic keratin. Hepatocellular carcinomas express only Cytokeratins 8 and 18. |
Synonyms | Cytokeratin-18, CK18, Keratin-18, Keratin 18, KRT18, CYK18, K18 |
Reference Data | |
Protein Pathways | Pathogenic Escherichia coli infection |
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