Desmoplakin (DSP) (2115-2132) Mouse Monoclonal Antibody [Clone ID: DP447]

Specifications

Product Data
Clone Name	DP447
Applications	IF, IHC, WB
Recommend Dilution	Immunoblotting Immunofluorescence Immunohistochemistry on frozen and Paraffin sections: Ready-to-use, with Paraffin use the microwave retrieval method.
Reactivity	Bovine, Chicken, Fish, Human, Mouse, Xenopus, Zebrafish
Host	Mouse
Clonality	Monoclonal
Immunogen	Synthetic peptide of human desmoplakin 2 (aa 2115-2132)
Specificity	The antibody shows distinct punctate membrane staining of different epithelia. Area compositae of the myocardium of higher vertebrates are also positive. The epitope is located in a region highly conserved among species (human, zebrafish). Reacts on several cultured cell lines: Human MCF-7, A-431, HaCaT, CaCo2; Bovine MDBK, BMGE; Rainbow trout RTG-2. Polypeptides reacting: Desmoplakin 1 and 2
Formulation	State: Supernatant State: Liquid culture supernatant containing 0.09% sodium azide
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	desmoplakin
Database Link	Entrez Gene 1832 Human UniProt ID P15924
Synonyms	DP, DSP, 250/210 kDa paraneoplastic pemphigus antigen
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Arrhythmogenic right ventricular cardiomyopathy (ARVC)

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