Helicobacter pylori (CagA Protein) Mouse Monoclonal Antibody [Clone ID: 3C10]
CAT#: AM09224PU-N
Helicobacter pylori (CagA Protein) mouse monoclonal antibody, clone 3C10, Aff - Purified
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CNY 6,120.00
货期*
4周
规格
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Specifications
Product Data | |
Clone Name | 3C10 |
Applications | ELISA |
Recommend Dilution | ELISA: Helicobacter pylori antibody (Clone 3C10) can be used as Detection antibody. In Sandwich ELISA, anti-HP CagA antibody clone 10E9 (Cat.-No AM09221PU-N) and anti-HP CagA antibody clone 5H10 (Cat.-No AM09222PU-N) coated wells match with HRP conjugated clone 3C10 to detect the recombinant antigen. HRP conjugated 3C10 also selectively detected cell lysate of a CagA containing HP strain when clone 10E9 was used as coating antibody. |
Reactivity | Helicobacter pylori |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | A highly immunogenic 32Kd CagA fragment, recombinant. |
Specificity | This antibody is raised against the H. pylori cytotoxin associated gene A protein (CagA). Reacts with the 32Kd recombinant Helicobacter pylori CagA. Cross reaction with other proteins has not been identified. |
Formulation | 0.01M PBS, pH 7.0 without preservatives State: Aff - Purified State: Lyophilized purified IgG fraction |
Reconstitution Method | Restore with Double distillated water to adjust the final concentration to 1.0 mg/ml. |
Purification | Affinity Chromatography on Protein G |
Conjugation | Unconjugated |
Storage Condition | Upon receipt, store (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
Background | Helicobacter pylori (H. pylori), a spiral rod shaped gram-negative bacterium, is frequently found in the stomach. In infected populations, 10-20% may develop gastritis and gastric ulcer and 1-2% may develop cancer. The genome of H. pylori isolates from carriers with symptoms contains a 40kb pathogenicity island encoding H. pylori cytotoxin, cytotoxin associated gene A protein (CagA) and other virulence associated factors. CagA is used as a biomarker for virulent H. pylori strains. |
Synonyms | H. pylori |
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