MUC16 Mouse Monoclonal Antibody [Clone ID: 23]

Specifications

Product Data
Clone Name	23
Applications	ELISA, FC, IF
Recommend Dilution	ELISA: 0.5 ng/ml or higher can recognize ELISA plates wells coated with CA125 at 5 international units per well.  Flow Cytometry: 10 μg/ml. Immunofluorescence: 10 μg/ml.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human CA125.
Specificity	Reactive with Human CA125.
Formulation	0.01M PBS, pH 7.2 without preservatives State: Aff - Purified State: Lyophilized purified Ig fraction
Reconstitution Method	Restore with Double distillated water to adjust the final concentration to 1.0 mg/ml.
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	mucin 16, cell surface associated
Database Link	Entrez Gene 94025 Human UniProt ID Q8WXI7
Background	Mucin16 (CA125) is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. It is a mullerian duct differentiation antigen that is overexpressed in epithelial ovarian cancer cells and secreted into the blood, although its expression is not entirely confined to ovarian cancer. Most biochemical studies have concluded that MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa with smaller subunits being described by some investigators.
Synonyms	MUC16, MUC-16, CA-125, CA 125
Reference Data

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