Growth Hormone (GH1) Mouse Monoclonal Antibody [Clone ID: YC8]

Specifications

Product Data
Clone Name	YC8
Applications	ELISA
Recommend Dilution	ELISA: This Biotin-conjugated monoclonal antibody can be used as a Tracer/Detection antibody in Sandwich ELISA applications for hGH detection in combination with a Capture Antibody Cat.-No DM1015. For detection use at 1:1,000 to 1:2,000
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified Recombinant hGH
Specificity	This monoclonal antibody reacts with natural and recombinant hGH.
Formulation	0.01M PBS, pH 7.2 Label: Biotin State: Liquid purified IgG fraction Stabilizer: 1% Gelatin Preservative: 0.1% Proclin-300
Purification	Affinity Chromatography on Protein G
Conjugation	Biotin
Storage Condition	Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	growth hormone 1
Database Link	Entrez Gene 2688 Human UniProt ID P01241
Background	Human growth hormone (hGH) plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. The effects of hGH in the body can be generally described as anabolic. It stimulates amino acid uptake and protein synthesis in muscle and other tissues. Growth Hormone (GH1) is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Genes for growth hormone (GH) are found in a gene cluster on 17q, which consists of two growth hormone genes and three CSH genes. The GHN1 gene is transcribed exclusively in the pituitary, whereas the other 4 genes are expressed only in placental tissues. Several isoforms of GH1 exist.
Synonyms	Pituitary growth hormone, Growth hormone 1, HGH
Reference Data
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Neuroactive ligand-receptor interaction

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