IL32 (1-131) Mouse Monoclonal Antibody [Clone ID: AT2F9]

Specifications

Product Data
Clone Name	AT2F9
Applications	ELISA, IF, WB
Recommend Dilution	ELISA. Western blot (1:500 - 1:1000). Immnocytochemistry / Immunoflourescence.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human IL32 (1-131aa) purified from E. coli
Specificity	The antibody recognizes human IL-32 at aa1-131. Other species not tested.
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	interleukin 32
Database Link	Entrez Gene 9235 Human UniProt ID P24001
Background	The gene encoding IL32 is located on human chromosome 16p13.3 and is organized into eight exons. IL32 is mainly expressed in natural killer cells, T cells, epithelial cells, and blood monocytes. It can induce the proinflammatory cytokines TNFα and IL1β in murine peritoneal macrophages as well as in phorbol ester-differentiated human THP1 cells. In the inflamed lesions of chronic pancreas, the ductal expression of IL32 was markedly increased. Pancreatic duct cells are the local source of IL32, and IL32 may play an important role in inflammatory responses and pancreatic cancer growth. Recently, a synergism between IL32 and other well characterized players in innate immunity has been documented.
Synonyms	IL-32, NK4, TAIF
Reference Data
Protein Families	Secreted Protein

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