CD56 (NCAM1) Mouse Monoclonal Antibody [Clone ID: 123C3.D5]

Specifications

Product Data
Clone Name	123C3.D5
Applications	IHC, WB
Recommend Dilution	Immunohistochemistry on Formalin-Fixed, Paraffin-Embedded Sections: 1/100 Pretreatment of deperaffinized tissue with heat-induced epitope retrieval is recommended. Use Polymer anti Mouse/Rabbit IgG as a detection system. Positive Control: Neuroblastoma, neuroendocrine carcinoma.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Membrane preparation of a small cell lung carcinoma.
Specificity	Recognizes CD56/NCAM-1. Cellular Localization: Cell membrane.
Formulation	State: Supernatant State: Liquid Tissue Culture Supernatant with 0.2% BSA and 15mM Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C.
Gene Name	neural cell adhesion molecule 1
Database Link	Entrez Gene 9332 HumanEntrez Gene 4684 Human UniProt ID P13591
Background	Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule which is glycosylated or sialylated to produce the mature species. NCAM (CD56) is reported to express on most neuroectodermal derived cell lines, tissues, and neoplasms such as retinoblastoma, medullblastoma, astrocytoma, and neuroblastoma. It is also expressed on some mesodermally derived tumors such as rhabdomyosarcoma and also on natural killer cells.
Synonyms	NCAM-1, N-CAM-1, NCAM
Reference Data
Protein Families	Druggable Genome, Secreted Protein, Transmembrane

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