CD46 Mouse Monoclonal Antibody [Clone ID: 3F1]

Specifications

Product Data
Clone Name	3F1
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA: 1/20000-1/100000. Western Blot: 1/2000-1/10002.  Flow Cytometry.  Immunohistochemistry.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant CD46 protein
Specificity	This antibody reacts with human 44 kDa CD46 protein. Diffuse and duplicated bands can be seen due to the glycosylation of CD46.
Formulation	PBS State: Purified State: Lyophilized purified antibody Preservative: None
Reconstitution Method	Restore in distilled water.
Concentration	lot specific
Purification	Protein A Chromatography
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month  or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Gene Name	CD46 molecule
Database Link	Entrez Gene 4179 Human UniProt ID P15529
Background	CD46 is one of the membrane complement regulatory proteins. CD46 possesses C3b-binding and factor I cofactor activities which play important roles in the regulation of the complement activation pathway. CD46 is widely distributed on blood cells, endothelial cells, epithelial cells and tumor cell lines. CD46 exists as many isoforms in a variety of tissues. The antigen has a broad distribution and is present on leukocytes, platelets, endothelial cells, epithelial cells and fibroblasts. It is strongly expressed on salivary gland ducts and kidney ducts, moderately on lymphocytes and endothelium, and weakly on interstitial tissues and muscle cells, but not on erythrocytes. It is expressed on thymocytes, B cells, monocytes, granulocytes, NK cells, platelets, epithelial and endothelial cells.
Synonyms	TLX, MIC10
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.