Myoferlin (MYOF) Mouse Monoclonal Antibody [Clone ID: 7D2]

Specifications

Product Data
Clone Name	7D2
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA. Western Blot: 1/50-1/5000. Immunohistochemistry: 1/20-1/1000.
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Synthetic peptide derived from N-term domain of the Human FER1L3 protein.
Specificity	This antibody reacts with Human 234 kDa FER1L3 protein. Cross reacts with Mouse protein.
Formulation	0.1M Tris, 0.1M Glycine, 2% Sucrose State: Purified State: Lyophilized purified antibody Preservative: None
Reconstitution Method	Restore in distilled water
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Gene Name	myoferlin
Database Link	Entrez Gene 26509 Human UniProt ID Q9NZM1
Background	Myoferlin belongs to the ferlin family and contains five C2 domains. It is a calcium/phospholipid binding protein that plays a role in the plasmalemma repair mechanism of endothelial cells that permits rapid resealing of membranes disrupted by mechanical stress. It is also involved in endocytic recycling and implicated in VEGF signal transduction by regulating the levels of the receptor KDR. Myoferlin is expressed in myoblast and endothelial cells (at protein level), highly expressed in cardiac and skeletal muscles, also present in lung and at very low levels in kidney, placenta and brain. There are eight named isoforms.
Synonyms	MYOF, FER1L3, KIAA1207
Reference Data

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