SYBL1 (VAMP7) Mouse Monoclonal Antibody [Clone ID: 158.2]

Specifications

Product Data
Clone Name	158.2
Applications	ELISA, FC, IF, IHC, WB
Recommend Dilution	ELISA. Western Blot: 1/500-1/2000.  Immunofluorescence.  Immunohistochemistry: 1/10-1/400.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	GST-TI-VAMP recombinant protein
Specificity	Reacts with Human 25 kDa TI-VAMP protein. Cross reacts with TI-VAMP from different species (Mouse, Rat, Canine).
Formulation	0.1M Tris, 0.1M Glycine, 2% Sucrose State: Purified State: Lyophilized purified powder Preservative: None
Reconstitution Method	Restore in distilled water.
Concentration	1.0 mg/ml after reconstitution
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month  or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Gene Name	vesicle associated membrane protein 7
Database Link	Entrez Gene 6845 Human UniProt ID P51809
Background	SYBL1 (Synaptobrevin-like 1) is found ubiquitously and is an unusual v-SNAREs molecule implicated in cellular exocytosis. The SYBL1 gene is found on the pseudoautosomal region (PAR) of X chromosome. It is a highly conserved gene and has been shown to be silenced on inactive X and Y chromosomes. In ICF syndrome, a human disease affecting DNA methylation, SYBL1 escapes from silencing and this correlates with the observed altered patterns of histone methylation and acetylation found. An association between some SYBL1 alleles and bipolar affective disorder (BPAD) has been observed.
Synonyms	VAMP7, Ti-VAMP, Vesicle-associated membrane protein 7
Reference Data

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