Double stranded DNA Mouse Monoclonal Antibody [Clone ID: 11B6]

Specifications

Product Data
Clone Name	11B6
Applications	ELISA, IHC
Recommend Dilution	ELISA.  Immunohistochemistry.
Host	Mouse
Clonality	Monoclonal
Immunogen	Double Stranded DNA
Specificity	Shows 100% reactivity to calf dsDNA and 5% to calf ssDNA.  Does not cross react with RNA.
Formulation	State: Supernatant State: Lyophilized powder (Cell Culture Supernatant) Preservative: None
Reconstitution Method	Restore in distilled water.
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month  or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Background	Deoxyribonucleic acid (DNA) is a long polymer of nucleotides that is held together by a backbone made of sugars and phosphate groups. It holds the genetic instructions for the development and function of living things. DNA is crucial for living organisms, and all known cellular life and some viruses contain DNA. In eukaryotes, DNA exists in the cell nucleus, while in prokaryotes, DNA is located in the cytoplasm. In living organisms, DNA does not usually exist as a single molecule, but instead as a tightly-associated pair of molecules in the shape of a right-handed double helix. The two DNA strands are held together by hydrogen bonds as well as forces generated by the hydrophobic effect and pi stacking.  During replication and transcription, portions of the helix unwind and become single stranded. These single-stranded DNA are surrounded by protective proteins. Double stranded (ds) DNA markers are useful tools in biology research and aid in the study of DNA behavior and characteristics.
Reference Data

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