Bad pSer155/118 Mouse Monoclonal Antibody [Clone ID: 27AT381]

Specifications

Product Data
Clone Name	27AT381
Applications	WB
Recommend Dilution	ELISA: 1/1,000. Western blotting1: 1/100-1/500.
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	This monoclonal antibody is generated from mice immunized with a KLH conjugated synthetic peptide corresponding to sequences in Ser155 region of mouse Bad and residue Ser155 is phosphorylated.
Specificity	This antibody is specific to mBad pSer155.
Formulation	PBS containing 0.09% (W/V) Sodium Azide as preservative. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	BCL2-associated agonist of cell death
Database Link	Entrez Gene 12015 Mouse UniProt ID Q61337
Background	Apoptosis is a critical aspect of cellular function and is implicated in a broad range of human diseases, from cancer to neurodegenerative and cardiovascular diseases. Intrafamilial Bcl-2 protein contacts are thought to regulate key aspects of apoptosis. The corruption of apoptotic instructions is associated with a large subset of human diseases, ranging from cancer and cardiovascular disease to neurodegenerative diseases, and name just a few. Understanding regulation of apoptosis is necessary to constructing a strategy for pharmaceutical intervention. The BH3 domain of Bcl-2 family members has been identified as key to the Bcl-2 regulatory function, although details are not fully elucidated.
Synonyms	BAD, BBC6, BCL2L8, Bcl-2-like protein 8, Bcl2-L-8
Reference Data

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