Sumo 1 (SUMO1) Mouse Monoclonal Antibody [Clone ID: 66AT1273.94]
CAT#: AM11043PU-N
Sumo 1 (SUMO1) mouse monoclonal antibody, clone 66AT1273.94, Purified
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CNY 6,589.00
货期*
5周
规格
Specifications
Product Data | |
Clone Name | 66AT1273.94 |
Applications | WB |
Recommend Dilution | ELISA: 1/1,000. Western blot: 1/100-1/500. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Purified recombinant GST-SUMO1 fusion protein |
Specificity | This antibody is specific to SUMO1. |
Formulation | PBS containing 0.09% (W/V) Sodium Azide as preservative State: Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Gene Name | small ubiquitin-like modifier 1 |
Database Link | |
Background | Covalent modification of target lysines by SUMO (small ubiquitin-like modifier) modulates processes such as protein localization, transcription, nuclear transport, mitosis, DNA replication and repair, signal transduction, and viral reproduction. SUMO does not seem to be involved in protein degradation and may in fact function as an antagonist of ubiquitin in the degradation process. The SUMO family consists of SUMO1 and closely related homologs SUMO2, SUMO3, and SUMO4. Sumoylation has been shown to regulate a wide range of proteins, including MDM2, PIAS, PML, RanGAP1, RanBP2, p53, p73, HIPK2, TEL, c-Jun, Fas, Daxx, TNFRI, Topo-I, Topo-II, PARK2, WRN, Sp100, IkB-alpha, Androgen receptor (AR), GLUT1/4, CaMK, DNMT3B, TDG, HIF1A, CHD3, EXOSC9, RAD51, and viral targets such as CMV-IE1/2, EBV-BZLF1, and HPV/BPV-E1. |
Synonyms | SMT3C, SMT3H3, UBL1, GMP1, SMT3 homolog 3, Sentrin |
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