TYRO3 Mouse Monoclonal Antibody [Clone ID: 64CT15.6.2.3.1]

Specifications

Product Data
Clone Name	64CT15.6.2.3.1
Applications	IHC, WB
Recommend Dilution	ELISA: 1/1,000. Western blotting: 1/100-1/1000. Immunohistochemistry 1/50-1/100.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	This antibody is generated from mouse immunized with human recombinant TYRO3 protein.
Specificity	This antibody is specific to TYRO3.
Formulation	PBS containing 0.09% (W/V) Sodium Azide as preservative. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	TYRO3 protein tyrosine kinase
Database Link	Entrez Gene 7301 Human UniProt ID Q06418
Background	Tyrosine kinase 3,mainly expressed in brain,is involved in the protection of neurons from apoptosis. Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
Synonyms	BYK, DTK, RSE, SKY
Reference Data

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