ENPP3 Mouse Monoclonal Antibody [Clone ID: NP4D6]
CAT#: AM12003FC-N
ENPP3 mouse monoclonal antibody, clone NP4D6, FITC
Conjugation: Unconjugated APC PE
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CNY 3,810.00
Specifications
Product Data | |
Clone Name | NP4D6 |
Applications | FC, IF |
Recommend Dilution | Flow Cytometry analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | HEK-293 cells transfected with human CD203c |
Specificity | This antibody reacts with CD203c, a transmembrane ectoenzyme expressed on basophils and mast cells, and overexpressed upon their activation. |
Formulation | Phosphate buffered saline (PBS) Label: FITC State: Liquid Ig fraction Stabilizer: 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) Preservative: 15 mM sodium azide |
Conjugation | FITC |
Storage Condition | Store the antibody at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. |
Gene Name | ectonucleotide pyrophosphatase/phosphodiesterase 3 |
Database Link | |
Background | CD203c, also known as ENPP-3, is integral membrane ectoenzyme (ectonucleotide pyrophosphatase/phosphodiesterase 3), that hydrolyses nucleotide triphosphates and thus modulates purinergic signaling. CD203c is expressed mainly on activated basophils and mast cells. CD203c is upregulated in response to IgE-receptor cross-linking and is overexpressed on neoplastic mast cells in patients with systemic mastocytosis. Measurement of its induced enhancement on the plasma membrane is useful for diagnostics of allergies. |
Synonyms | E-NPP 3, PDNP3, Phosphodiesterase I beta, PD-I beta |
Reference Data |
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