PDGF Receptor alpha (PDGFRA) Mouse Monoclonal Antibody [Clone ID: 16A1]

CAT#: AM12068AC-N

PDGF Receptor alpha (PDGFRA) mouse monoclonal antibody, clone 16A1, APC

Conjugation: Unconjugated APC Biotin PE



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CNY 4,340.00


货期*
5周

规格
    • 100 Tests

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Specifications

Product Data
Clone Name 16A1
Applications FC
Recommend Dilution Flow Cytometry: 10 µl reagent / 100 µl of whole blood or 10e6 cells in a suspension.
The content of a vial (1 ml) is sufficient for 100 Tests.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen CD140a-transfected NIH 3T3 cells
Specificity This Mouse monoclonal antibody 16A1 recognizes CD140a / PDGF-RA, the 170 kDa alpha chain of platelet-derived growth factor receptor, which is widely expressed on a variety of mesenchymal-derived cells and plays pro-proliferative or anti-proliferative roles in various tumours.
Formulation PBS
Label: APC
State: Liquid purified Ig fraction
Stabilizer: 0.2% (w/v) high-grade BSA (Protease free)
Preservative: 15 mM Sodium Azide
Label: Allophycocyanin
Purification Size-Exclusion Chromatography
Conjugation APC
Storage Condition Store the antibody undiluted at 2-8°C.
DO NOT FREEZE!
This product is photosensitive and should be protected from light.
Gene Name platelet derived growth factor receptor alpha
Background CD140a / PDGF-RA (platelet-derived growth factor receptor alpha) is a cell surface receptor for members of platelet-derived growth factor family, whose intracellular part contains a tyrosine kinase domain. CD140a forms homodimers, or heterodimerizes with CD140b / PDGF-RB. Whereas CD140b induces in different cell types their proliferation and migration, the role of CD140a is more controversial, with pro-proliferative or anti-proliferative effects. CD140a has early developmental functions, mediates mesodermal cell migration, and later acts in signaling associated in epithelial-mesenchymal interactions.
Synonyms PDGF-R-alpha, PDGF Receptor alpha
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase, Transmembrane
Protein Pathways Calcium signaling pathway, Colorectal cancer, Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion, Gap junction, Glioma, MAPK signaling pathway, Melanoma, Pathways in cancer, Prostate cancer, Regulation of actin cytoskeleton
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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