Bone Sialoprotein (IBSP) (CD-BSP 108-122) Rat Monoclonal Antibody [Clone ID: IDBSP5]
CAT#: AM20240PU-N
Bone Sialoprotein (IBSP) (CD-BSP 108-122) rat monoclonal antibody, clone IDBSP5, Purified
Size: 10 ug
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CNY 7,447.00
货期*
5周
规格
Specifications
Product Data | |
Clone Name | IDBSP5 |
Applications | ELISA, WB |
Recommend Dilution | ELISA: 1/2000. Western Blot. |
Reactivity | Human |
Host | Rat |
Clonality | Monoclonal |
Immunogen | Recombinant Human CD-BSP (108-122) |
Specificity | Recognizes Carbohydrate-deficient Bone Sialoprotein (CD-BSB/Tumor-BSP). |
Formulation | PBS, pH 7.4 State: Purified State: Liquid purifed IgG fraction |
Purification | Protein G Chromatography |
Conjugation | Unconjugated |
Storage Condition | Store the antibody at -20°C. Avoid repeated freezing and thawing. |
Gene Name | integrin binding sialoprotein |
Database Link | |
Background | The protein encoded by the Bone Sialoprotein gene is a major structural protein of the bone matrix. It is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts, and it constitutes approximately 12% of the noncollagenous proteins in human bone. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor. |
Synonyms | Bone sialoprotein II, BSP II, IBSP, BNSP |
Reference Data | |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | ECM-receptor interaction, Focal adhesion |
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