Trypsin (PRSS1) Mouse Monoclonal Antibody

Specifications

Product Data
Clone Name	TRYP11‑224.3
Applications	ELISA, IHC
Recommend Dilution	ELISA: 1/12500. Immunohistochemistry on Paraffin Sections: 10 µg/ml.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified Human pancreatic Trypsin.
Specificity	Specifically recognizes pancreatic Trypsin. Does not cross-react with pancreatic Chymotrypsin. May be used in immunoassays to detect and quantitate pancreatic Trypsin.
Formulation	PBS, pH 7.4 State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein G Chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	protease, serine 1
Database Link	Entrez Gene 5644 Human UniProt ID P07477
Background	Trypsin is a 24 kDa enzyme of the serine proteinase family. It is produced in the pancreas as an inactive precursor, trypsinogen, but the active enzyme is located in the gastrointestinal tract where it degrades proteins to large peptides. Trypsin prefers lysine and arginine residues. One of the substrates for trypsin is chymotrypsinogen which is cleaved to produce active chymotrypsin. High levels of immunoreactive trypsin in the bloodstream can indicate pancreatic malfunction and this indicator is used to screen for and diagnose Cystic Fibrosis.
Synonyms	Beta-trypsin; MGC120175; MGC149362; TRP1; TRY1; TRY4; TRYP1
Reference Data

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